Université de Bordeaux (Institut des Sciences Moléculaires, UMR 5255), Talence.
MCF dans le groupe Catalysis, Synthesis and Health, équipe du Pr. E. Fouquet.
Méthodologies en chimie organique pour le marquage de biomolécules
07/02/2020 : Habilitation à Diriger des Recherches
Enseignements : TD en Chimie Générale/Organique (L1-L3), TP de Chimie Organique (M1), cours de chimie Organométallique (M1), cours de Chimie Industrielle (M2)
2011 - 2012
Université de Versailles – St Quentin en Yvelines (Institut Lavoisier, UMR 8180), Versailles.
A.T.E.R. dans l’équipe du Pr. C. Greck.
Organocatalyse
Enseignement : TD en Chimie Générale (L1) et TP en Chimie Organique/Inorganique (L1-L3)
2010 - 2011
Aarhus Universitet – Department of Chemistry, Aarhus, Danemark.
Post-doctorat dans l’équipe du Pr. T. Skrydstrup.
Chimie organométallique
2006 - 2009
Institut de Chimie des Substances Naturelles (ICSN-CNRS UPR2301), Gif-sur-Yvette.
Master et thèse sous la direction du Dr. R. H. Dodd.
Chimie hétérocyclique et médicinale
Enseignement : TP, Moniteur à l’Ecole Polytechnique, Palaiseau
Contact
philippe.hermange@u-bordeaux.fr
351 Cours de la Libération / 33405 Talence Cedex / France
Brevets
- Complexes de cycloheptyne-cobalt carbonyles et leurs applications en bioconjugaison, P. Hermange, M. Cormier, E. Fouquet, 2018, PA FR18 58749, PCT/FR2019/052235.
- System providing controlled delivery of gaseous CO for carbonylation reactions, P. Hermange, R. Taaning, S. D. Friis, A.T. Lindhart, T. Skrydstrup, 2010, PA 201070546, 1400002233.
Publications
Doussot, A., Fouquet, E., Hermange, P. (). Syntheses of [17O]Aryl Sulfoxides, Selenoxides, Phosphine Oxides, and Arsine Oxide by Photo-oxidation Using [17O2]Dioxygen Generated Ex Situ. In Organic Letters (Vol. 27, Issue 27, p. 7331-7335). https://doi.org/10.1021/acs.orglett.5c01979
Dahiya, A., Dhara, K., Garo, J., Gicquiaud, J., Karnat, A., Berlande, M., Hermange, P., Sotiropoulos, J.M., Toullec, P.Y. (). Brønsted Acid-Catalyzed Enantioselective and Para-Selective Addition of Phenols to 1-Alkynylnaphth-2-Ols. In Advanced Synthesis and Catalysis (Vol. 367, Issue 8, p. e202401457). https://doi.org/10.1002/adsc.202401457
Steffann, M., Bluet, G., Roy, S., Aubert, C., Fouquet, E., Hermange, P. (). 18F-Fluorination of a supported 2-(aryl-di-tert-butylsilyl)-N-methyl-imidazole for indirect 18F-labeling of a VHH single-variable domain. In Journal of Labelled Compounds and Radiopharmaceuticals (Vol. 67, Issue 3, p. 104-110). https://doi.org/10.1002/jlcr.4082
Doussot, A., Bakaï, M.F., Fouquet, E., Hermange, P. (). Ex Situ Generation of 18O2 and 17O2 from Endoperoxides for *O-Labeling and Mechanistic Studies of Oxidations by Dioxygen. In Organic Letters (Vol. 25, Issue 25, p. 4661-4665). https://doi.org/10.1021/acs.orglett.3c01487
Steffann, M., Tisseraud, M., Bluet, G., Roy, S., Aubert, C., Fouquet, E., Hermange, P. (). Last-step 18F-fluorination of supported 2-(aryl-di-tert-butylsilyl)-N-methyl-imidazole conjugates for applications in positron emission tomography. In Chemical Communications (Vol. 58, Issue 65, p. 9140-9143). https://doi.org/10.1039/d2cc03258a
Cormier, M., Tabey, A., Christine, T., Audrain, H., Fouquet, E., Hermange, P. (). Synthesis and [*C]CO-labelling of (C,N)gem-dimethylbenzylamine-palladium complexes for potential applications in positron emission tomography. In Dalton Transactions (Vol. 50, Issue 30, p. 10608-10614). https://doi.org/10.1039/d1dt01633d
Gicquiaud, J., Abadie, B., Dhara, K., Berlande, M., Hermange, P., Sotiropoulos, J.M., Toullec, P.Y. (). Brønsted Acid-Catalyzed Enantioselective Cycloisomerization of Arylalkynes. In Chemistry A European Journal (Vol. 26, Issue 69, p. 16266-16271). https://doi.org/10.1002/chem.202003783
Tabey, A., Christine, T., Fouquet, E., Hermange, P. (). Practical synthesis of 13C-labeled conjugates by [13C]CO-carbonylation of supported arylbipyridylpalladium complexes and alkyne–azide cycloadditions. In Applied Organometallic Chemistry (Vol. 34, Issue 9, p. e5779). https://doi.org/10.1002/aoc.5779
Christine, T., Tabey, A., Cornilleau, T., Fouquet, E., Hermange, P. (). Syntheses of o-iodobenzyl alcohols‒BODIPY structures as potential precursors of bimodal tags for positron emission tomography and optical imaging. In Tetrahedron (Vol. 75, Issue 52, p. 130765). https://doi.org/10.1016/j.tet.2019.130765
Cormier, M., Fouquet, E., Hermange, P. (). Expedient synthesis of a symmetric cycloheptyne-Co2(CO)6 complex for orthogonal Huisgen cycloadditions. In Organic Chemistry Frontiers (Vol. 6, Issue 8, p. 1114-1117). https://doi.org/10.1039/c9qo00086k
Tabey, A., Audrain, H., Fouquet, E., Hermange, P. (). Bioconjugated arylpalladium complexes on solid supports for a convenient last-step synthesis of 11C-labelled tracers for positron emission tomography. In Chemical Communications (Vol. 55, Issue 53, p. 7587-7590). https://doi.org/10.1039/c9cc03215k
Tisseraud, M., Schulz, J., Vimont, D., Berlande, M., Fernandez, P., Hermange, P., Fouquet, E. (). Highly hindered 2-(aryl-di-tert -butylsilyl)- N -methyl-imidazoles: A new tool for the aqueous 19F- and 18F-fluorination of biomolecule-based structures. In Chemical Communications (Vol. 54, Issue 40, p. 5098-5101). https://doi.org/10.1039/c8cc01782d
Tabey, A., Berlande, M., Hermange, P., Fouquet, E. (). Mechanistic and asymmetric investigations of the Au-catalysed cross-coupling between aryldiazonium salts and arylboronic acids using (P,N) gold complexes. In Chemical Communications (Vol. 54, Issue 91, p. 12867-12870). https://doi.org/10.1039/c8cc07530a
Cornilleau, T., Simonsen, M., Vang, M., Taib-Maamar, N., Dessolin, J., Audrain, H., Hermange, P., Fouquet, E. (). Last-Step Pd-Mediated [11C]CO Labeling of a Moxestrol-Conjugated o-Iodobenzyl Alcohol: From Model Experiments to in Vivo Positron Emission Tomography Studies. In Bioconjugate Chemistry (Vol. 28, Issue 11, p. 2887-2894). https://doi.org/10.1021/acs.bioconjchem.7b00583
Tabey, A., Mendy, J., Hermange, P., Fouquet, E. (). Bipyridyl– and pyridylquinolyl–phenothiazine structures as potential photoactive ligands: Syntheses and complexation to palladium. In Tetrahedron Letters (Vol. 58, Issue 32, p. 3096-3100). https://doi.org/10.1016/j.tetlet.2017.06.073
Cornilleau, T., Hermange, P., Fouquet, E. (). Gold-catalysed cross-coupling between aryldiazonium salts and arylboronic acids: Probing the usefulness of photoredox conditions. In Chemical Communications (Vol. 52, Issue 65, p. 10040-10043). https://doi.org/10.1039/c6cc04239b
Cornilleau, T., Audrain, H., Guillemet, A., Hermange, P., Fouquet, E. (). General last-step labeling of biomolecule-based substrates by [12C], [13C], and [11C] carbon monoxide. In Organic Letters (Vol. 17, Issue 2, p. 354-357). https://doi.org/10.1021/ol503471e
