Conférence
Proactive Biosensing for Continuous Health Monitoring
Koji Toma
College of Engineering, Shibaura Institute of Technology (Tokyo, Japan)
On 3 November 2025, 11 am.
ENSMAC, amphi 3
Continuous tracking of biochemical dynamics is a critical requirement for advanced health monitoring, especially when analyte concentrations change rapidly. Despite the inherent high sensitivity and selectivity of biosensors, their long-term continuous operation remains challenging due to the need for sensor regeneration. This talk will introduce two biosensing platforms that address these limitations.
The first is a gas detection system designed to measure volatile organic compounds (VOCs) emitted from the external ear. By capturing ear-derived gases, this approach provides non-invasive and continuous access to blood-related biomarkers. Its operational principles and potential applications in daily health monitoring will be described.
The second is a surface plasmon resonance (SPR) biosensor tailored for real-time drug monitoring. Using an aptamer as the recognition element, the sensor enables reversible binding and dissociation of drugs in the same solution, thereby eliminating the requirement for additional regeneration. The design principles, operating mechanism, and prospective applications of this biosensor will be presented.
These case studies highlight engineering strategies for realizing practical, continuous, and non-invasive biosensing systems.