Dernière modification : 13 janvier 2021

  • Chargé de recherche CNRS


    2015 : HDR de Chimie Physique, Univ. Bordeaux.
    2005 : Doctorat de Chimie Organique, UJF Grenoble.
    2002 : DEA de Chimie Moléculaire & Magistère de Chimie-Biologie, UJF Grenoble.
    2000 : Licence de Chimie, UJF Grenoble.

    Expérience professionnelle

    2010– : Chargé de Recherche CNRS, Institut des Sciences Moléculaires, Groupe NSYSA, Bordeaux.
    2008–2010  : Post-doctorat (EPRSC), UoL Liverpool, Chimie de Surface des Nanoparticules (Pr. M. J. Rosseinsky).
    2006–2008  : Post-doctorat (Bourse Marie Curie), UoL Liverpool, Antennes Moléculaires Peptidiques (Pr. R. J. Nichols).
    2005–2006  : Post-doctorat (programme européen), LEOPR, UJF Grenoble, Immuno-Capteurs Rédox & Interfaces Nano-Biotechnologiques (Dr. S. Cosnier).
    2002–2005  : Doctorat de Chimie Organique (bourse ministérielle), LEDSS, UJF Grenoble, Synthèse & Propriétés d’Intercalants de l’ADN (Dr. M. Demeunynck).

    Domaines de recherche

    > Electrochimie Moléculaire, Relation Structure/Activité.
    > Chimie Electroanalytique, Bioélectrochimie & Biocapteurs.
    > Electrochimie Bipolaire & Chimie des Matériaux.
    > Electrochimiluminescence.
    > Microscopie de Fluorescence Confocale à Balayage Laser.



    78. B. Gupta, L. Zhang, A. A. Melvin, B. Goudeau, L. Bouffier, A. Kuhn
    Designing Tubular Conducting Polymer Actuators for Wireless Electropumping
    Chemical Science 2021, sous presse.

    77. H. Li, R. Duwald, S. Pascal, S. Voci, C. Besnard, J. Bosson, L. Bouffier, J. Lacour, N. Sojic
    Near-Infrared Electrochemiluminescence in Water through Regioselective Sulfonation of Diaza [4] and [6]helicene Dyes [INSIDE FRONT COVER]
    Chemical Communications 2020, 56, 9771.

    76. L. Bouffier, N. Sojic
    Quantum nuts : two shells are better than one to achieve highly efficient electrochemiluminescence
    ACS Central Science 2020, 6, 1043.

    75. G. Salinas, A. L. Dauphin, S. Voci, L. Bouffier, N. Sojic, A. Kuhn
    Asymmetry controlled dynamic behavior of autonomous chemiluminescent Janus microswimmers
    Chemical Science 2020, 11, 7438.

    74. S. Voci, F. Zinna, L. Arrico, S. Grass, L. Bouffier, J. Lacour, L. Di Bari, N. Sojic
    Chiroptical Detection of a Model Ruthenium Dye in Water by Circularly Polarized-Electrochemiluminescence
    Chemical Communications 2020, 56, 5989.

    73. S. Voci, R. Duwald, S. Grass, D. J. Hayne, L. Bouffier, P. S. Francis, J. Lacour, N. Sojic
    Self-Enhanced Multicolor Electrochemiluminescence by Competitive Electron-transfer Processes
    Chemical Science 2020, 11, 4508.

    72. B. Tassy, A. L. Dauphin, H. M. Man, H. Le Guenno, E. Lojou, L. Bouffier, A. de Poulpiquet
    In situ 3D fluorescence tomography enables visualizing enzymatic O2-reduction at the electrochemical interface
    Analytical Chemistry 2020, 92, 7249.

    71. G. Salinas, A. L. Dauphin, C. Colin, E. Villani, S. Arbault, L. Bouffier, A. Kuhn
    Chemo‐and magnetotaxis of self‐propelled light emitting chemo‐electronic swimmers
    Angewandte Chemie International Edition 2020, 59, 7508.

    70. A. L. Dauphin, S. Arbault, A. Kuhn, N. Sojic, L. Bouffier
    Remote actuation of a light-emitting device based on magnetic stirring and wireless electrochemistry [COVER FEATURE]
    ChemPhysChem 2020, 21, 600.

    69. T. Bombail, P. Garrigue, B. Goudeau, D. Talaga, L. Bouffier, S. Bonhommeau, L. Servant, D. Zigah, S. Arbault, N. Sojic
    Dual microelectrodes decorated with nanotip arrays : Fabrication, characterization and spectroelectrochemical sensing
    Electrochimica Acta 2019, 328, 135105.

    68. A. L. Dauphin, A. Akchach, S. Voci, A. Kuhn, G. Xu, L. Bouffier, N. Sojic
    Tracking magnetic rotating objects by bipolar electrochemiluminescence
    Journal of Physical Chemistry Letters 2019, 10, 5318.

    67. L. Bouffier, D. Manojlovic, A. Kuhn, N. Sojic
    Advances in bipolar electrochemiluminescence for the detection of biorelevant targets
    Current Opinion in Electrochemistry 2019, 16, 28.

    66. F. Zinna, S. Voci, L. Arrico, E. Brun, A. Homberg, L. Bouffier, T. Funaioli, J. Lacour, N. Sojic, L. Di Bari
    Circularly polarized-electrochemiluminescence from a chiral bispyrene organic macrocycle
    Angewandte Chemie International Edition 2019, 58, 6952.

    65. I. Malytska, T. Doneux, M. Bougouma, A. Kuhn, L. Bouffier
    Wireless addressing of free-standing MoSe2 bipolar macro- and microparticles by bipolar electrochemistry [FRONT COVER]
    Journal of Physical Chemistry C 2019, 123, 5647.

    64. A. de Poulpiquet, B. Goudeau, P. Garrigue, N. Sojic, S. Arbault, T. Doneux, L. Bouffier
    A Snapshot of the electrochemical reaction layer by using 3 dimensionally resolved fluorescence mapping [BACK COVER]
    Chemical Science 2018, 9, 6622.

    63. V. Pirenne, G. Kurtay, S. Voci, L. Bouffier, N. Sojic, F. Robert, D. M. Bassani, Y. Landais
    Eosin-mediated alkylsulfonyl-cyanation of olefins
    Organic Letters 2018, 20, 4521.

    62. I. Hernández Delgado, S. Pascal, C. Besnard, S. Voci, L. Bouffier, N. Sojic, J. Lacour
    C-Functionalized Cationic Diazaoxa Triangulenes : Late-Stage Synthesis and Tuning of Physicochemical Properties
    Chemistry - A European Journal 2018, 24, 10186.

    61. L. Bouffier, N. Sojic, A. Kuhn
    Physical and nanoelectrochemistry : Current hot-spots and some more exotic topics
    Current Opinion in Electrochemistry 2018, 7, A1.

    60. S. Sangtarash, A. Vezzoli, H. Sadeghi, N. Ferri, H. M. O’Brien, I. Grace, L. Bouffier, R. J. Nichols, S. J. Higgins, C. J. Lambert
    Gateway state-mediated, long-range tunnelling in molecular wires
    Nanoscale 2018, 10, 3060.

    59. J. Gao, S. Chen, F. Altal, S. Hu, L. Bouffier, G. Wantz
    Bipolar Electrode Array Embedded in a Polymer Light-Emitting Electrochemical Cell
    ACS Applied Materials & Interfaces 2017, 9, 32405.

    58. Z. A. Fattah, L. Bouffier, A. Kuhn
    Indirect bipolar electrodeposition of polymers for the controlled design of zinc microswimmers [FRONT COVER]
    Applied Materials Today 2017, 9, 259.

    57. L. Bouffier, T. Doneux
    Coupling electrochemistry with in situ fluorescence (confocal) microscopy
    Current Opinion in Electrochemistry 2017, 6, 31.

    56. I. Malytska, C. Mézière, M. Keilar, L. Hirsch, G. Wantz, N. Avarvari, A. Kuhn, L. Bouffier
    Bipolar Electrochemistry with Organic Single Crystals for Wireless Synthesis of Metal-Organic Janus Objects and Asymmetric Photovoltage Generation
    Journal of Physical Chemistry C 2017, 121, 12921.

    55. L. Bouffier, S. Reculusa, V. Ravaine, A. Kuhn
    Modulation of Wetting Gradients by Tuning the Interplay between Surface Structuration and Anisotropic Molecular Layers with Bipolar Electrochemistry [FRONT COVER & COVER PROFILE]
    ChemPhysChem 2017, 18, 2637.

    54. L. Bouffier, N. Sojic, A. Kuhn
    Capillary-assisted bipolar electrochemistry : a focused minireview [FRONT COVER]
    Electrophoresis 2017, 38, 2687.

    53. H. Li, L. Bouffier, S. Arbault, A. Kuhn, C. F. Hogan, N. Sojic
    Spatially-resolved multicolor bipolar electrochemiluminescence
    Electrochemistry Communications 2017, 77, 10.

    52. H. Li, S. Voci, A. Wallabregue, C. Adam, G. M. Labrador, R. Duwald, I. Hernandez Delgado, S. Pascal, J. Bosson, J. Lacour, L. Bouffier, N. Sojic
    Efficient Annihilation Electrochemiluminescence of Cationic Helicene Luminophores
    ChemElectroChem 2017, 4, 1750.

    51. H. Li, A. Wallabregue, C. Adam, G. M. Labrador, J. Bosson, L. Bouffier, J. Lacour, N. Sojic
    Bright Electrochemiluminescence Tunable in the Near-infrared of Chiral Cationic Helicene
    Journal of Physical Chemistry C 2017, 121, 785.

    50. J. Bosson, G. M. Labrador, S. Pascal, F.-A. Miannay, O. Yushchenko, H. Li L. Bouffier, N. Sojic, R. C. Tovar, G. Muller, D. Jacquemin, A. D. Laurent, B. Le Guennic, E. Vauthey, J. Lacour
    Physicochemical and Electronic Properties of Cationic [6]Helicenes, from Chemical and Electrochemical Stabilities to Far-Red (Polarized) Luminescence [HOT PAPER & FRONT COVER]
    Chemistry - A European Journal 2016, 22, 18394.

    49. P. Lefrançois, V. S. R. Vajrala, I. Bonifas-Arredondo, B. Goudeau, T. Doneux, L. Bouffier, S. Arbault
    Direct oxidative pathway from amplex red to resorufin revealed by in-situ confocal imaging [INSIDE FRONT COVER]
    Physical Chemistry Chemical Physics 2016, 18, 25817.

    48. A. de Poulpiquet, B. Diez-Buitrago, M. Milutinovic, M. Sentic, S. Arbault, L. Bouffier, A. Kuhn, N. Sojic
    Dual enzymatic detection by bulk electrogenerated chemiluminescence
    Analytical Chemistry 2016, 88, 6585.

    47. T. Doneux, L. Bouffier, B. Goudeau, S. Arbault
    Coupling Electrochemistry with Fluorescence Confocal Microscopy to Investigate Electrochemical Reactivity. A Case Study with the Resazurin-Resorufin Fluorogenic Couple
    Analytical Chemistry 2016, 88, 6292.

    46. H. Li, P. Garrigue, L. Bouffier, S. Arbault, A. Kuhn, N. Sojic
    Wireless generation and remote readout of electrochemiluminescence at the tip of an optical fiber
    Analyst 2016, 141, 4299.

    45. L. Bouffier, S. Arbault, A. Kuhn, N. Sojic
    Generation of electrochemiluminescence at bipolar electrodes : concept and applications
    Analytical and Bioanalytical Chemistry 2016, 408, 7003.

    44. A. Martin, L. Bouffier, K. B. Grant, B. Limoges, D. Marchal
    Real-time electrochemical LAMP : a rational comparative study of different DNA intercalating and non-intercalating redox probes
    Analyst 2016, 141, 4196.

    43. L. Bouffier, V. Ravaine, N. Sojic, A. Kuhn
    Electric Fields for Generating Unconventional Motion of Small Objects
    Current Opinion in Colloid and Interface Science 2016, 21, 57.

    42. C. Adam, A. Wallabregue, H. Li, J. Gouin, R. Vanel, S. Grass, J. Bosson, L. Bouffier, J. Lacour, N. Sojic
    Electrogenerated Chemiluminescence of Cationic Triangulene Dyes : Crucial Influence of the Core Heteroatoms
    Chemistry - A European Journal 2015, 21, 19243.

    41. A. de Poulpiquet, B. Diez-Buitrago, M. Milutinovic, B. Goudeau, L. Bouffier, S. Arbault, A. Kuhn, N. Sojic
    Dual-Color Electrogenerated Chemiluminescence from Dispersions of Conductive Micro-Beads Addressed by Bipolar Electrochemistry
    ChemElectroChem 2016, 3, 404.

    40. S. Chen, G. Wantz, L. Bouffier, J. Gao
    Solid-State Bipolar Electrochemistry : Polymer-Based Light-Emitting Electrochemical Cells [BACK COVER]
    ChemElectroChem 2016, 3, 392.

    39. G. Tisserant, J. Gillion, J. Lannelongue, Z. Fattah, P. Garrigue, J. Roche, D. Zigah, A. Kuhn, L. Bouffier
    Single-Step Screening of the Potential Dependence of Metal Layer Morphologies Along Bipolar Electrodes
    ChemElectroChem 2016, 3, 387.

    38. M. Sentic, S. Arbault, L. Bouffier, D. Manojlovic, A. Kuhn, N. Sojic
    3D Electrogenerated Chemiluminescence : from Surface-Confined Reactions to Bulk Emission [BACK COVER]
    Chemical Science 2015, 6, 4433.

    37. G. Tisserant, Z. Fattah, C. Ayela, J. Roche, B. Plano, D. Zigah, B. Goudeau, A. Kuhn, L. Bouffier
    Generation of Metal Composition Gradients by Means of Bipolar Electrodeposition
    Electrochimica Acta 2015, 179, 276.

    36. J. Roche, S. Carrara, J. Sanchez, J. Lannelongue, G. Loget, L. Bouffier, P. Fischer, A. Kuhn
    Wireless Powering of e-Swimmers
    Scientific Reports 2014, 4, 6705.

    35. M. Sentic, S. Arbault, B. Goudeau, D. Manojlovic, A. Kuhn, L. Bouffier, N. Sojic
    Electrochemiluminescent Swimmers for Dynamic Enzymatic Sensing [INSIDE FRONT COVER]
    Chemical Communications 2014, 50, 10202-10205.

    34. L. Bouffier, T. Doneux, B. Goudeau, A. Kuhn
    Imaging Redox Activity at Bipolar Electrodes by Indirect Fluorescence Modulation
    Analytical Chemistry 2014, 86, 3708-3711.

    33. S. Kong, O. Fontaine, J. Roche, L. Bouffier, A. Kuhn, D. Zigah
    Electropolymerization of Polypyrrole by Bipolar Electrochemistry in an Ionic Liquid
    Langmuir 2014, 30, 2973-2976.

    32. J. Roche, G. Loget, D. Zigah, Z. Fattah, B. Goudeau, S. Arbault, L. Bouffier, A. Kuhn
    Straightforward Synthesis of Ringed Particles
    Chemical Science 2014, 5, 1961-1966.

    31. L. Bouffier, B. Wang, A. Roget, T. Livache, M. Demeunynck, P. Mailley
    Indirect Detection of DNA Hybridization at Modified Electrodes by Using an Electroactive Pyridoacridone Intercalator
    Analytical and Bioanalytical Chemistry 2014, 406, 1163-1172.

    30. L. Bouffier, D. Zigah, C. Adam, M. Sentic, Z. Fattah, D. Manojlovic, A. Kuhn, N. Sojic
    Lighting up Redox Propulsion with Luminol Electrogenerated Chemiluminescence
    ChemElectroChem 2014, 1, 95-98.

    29. G. Loget, D. Zigah, L. Bouffier, N. Sojic, A. Kuhn
    Bipolar Electrochemistry : from Materials Science to Motion and Beyond
    Accounts of Chemical Research 2013, 46, 2513-2523.

    28. H. H. P. Yiu, L. Bouffier, P. Boldrin, J. Long, J. B. Claridge, M. J. Rosseinsky
    Comprehensive Study of DNA Binding onto Iron(II,III) Oxide Nanoparticles with a Positively Charged Polyamine 3-D Coating
    Langmuir 2013, 29, 11354-11365.

    27. Z. Fattah, P. Garrigue, B. Goudeau, V. Lapeyre, A. Kuhn, L. Bouffier
    Capillary Electrophoresis as a Production Tool for Asymmetric Microhybrids
    Electrophoresis 2013, 34, 1985-1990.

    26. Z. Fattah, J. Roche, P. Garrigue, D. Zigah, L. Bouffier, A. Kuhn
    Localized Chemiluminescence from Asymmetric Inorganic Surface Layers Generated by Bipolar Electrochemistry
    ChemPhysChem 2013, 14, 2089-2093.

    25. L. Bouffier, A. Kuhn
    Design of a Wireless Electrochemical Valve
    Nanoscale 2013, 5, 1305-1309.

    24. S. P. Valappil, H. H. P. Yiu, L. Bouffier, C. K. Hope, G. Evans, J. B. Claridge, S. M. Higham, M. J. Rosseinsky
    Effect of Novel Antibacterial Gallium-Carboxymethyl Cellulose on Pseudomonas Aeruginosa [BLOG HIGHLIGHT]
    Dalton Transactions 2013, 42, 1778-1786.

    23. G. Loget, J. Roche, E. Gianessi, L. Bouffier, A. Kuhn
    Indirect Bipolar Electrodeposition
    Journal of the American Chemical Society 2012, 134, 20033-20036.

    22. L. Bouffier, I. Gosse, M. Demeunynck, P. Mailley
    Electrochemistry and Bioactivity Relationship of 6-Substituted-4H-Pyrido[4,3,2-kl]acridin-4-one Antitumor Drug Candidates
    Bioelectrochemistry 2012, 88, 103-109.

    21. Z. Fattah, P. Garrigue, V. Lapeyre, A. Kuhn, L. Bouffier
    Controlled Orientation of Asymmetric Copper Deposits on Carbon Microobjects by Bipolar Electrochemistry
    Journal of Physical Chemistry C 2012, 116, 22021-22027.

    20. M. Heim, L. Rousseau, S. Reculusa, V. Urbanova, C. Mazzocco, S. Joucla, L. Bouffier, K. Vytras, P. Bartlett, A. Kuhn, B. Yvert
    Combined Macro-/Mesoporous Microelectrode Arrays for Low-Noise Extracellular Recording of Neural Networks
    Journal of Neurophysiology 2012, 108, 1793-1803.

    19. L. Bouffier, K. Lister, S. J. Higgins, R. J. Nichols, T. Doneux
    Electrochemical Investigations of Dissolved and Surface Immobilised 2-Amino-1,4-naphthoquinones in Aqueous Solutions
    Journal of Electroanalytical Chemistry 2012, 664, 80-87.

    18. Z. Fattah, G. Loget, V. Lapeyre, P. Garrigue, C. Warakulwit, J. Limtrakul, L. Bouffier, A. Kuhn
    Straightforward Single-Step Generation of Microswimmers by Bipolar Electrochemistry
    Electrochimica Acta 2011, 56, 10562-10566.

    17. C. I. Olariu, H. H. P. Yiu, L. Bouffier, T. Nedjadi, E. Costello, S. R. Williams, C. M. Halloran, M. J. Rosseinsky
    Multifunctional Fe3O4 Nanoparticles for Targeted Bi-Modal Imaging of Pancreatic Cancer
    Journal of Materials Chemistry 2011, 21, 12650-12659.

    16. L. Bouffier, H. H. P. Yiu, M. J. Rosseinsky
    Chemical Grafting of a DNA Intercalator Probe onto Functional Iron Oxide Nanoparticles : a Physicochemical Study
    Langmuir 2011, 27, 6185-6192.

    15. L. Scullion, T. Doneux, L. Bouffier, D. G. Fernig, S. J. Higgins, D. Bethell, R. J. Nichols
    Large Conductance Changes in Peptide Single Molecule Junctions Controlled by pH
    Journal of Physical Chemistry C 2011, 115, 8361-8368.

    14. R. E. Ionescu, C. Gondran, L. Bouffier, N. Jaffrezic-Renault, C. Martelet, S. Cosnier
    Label-Free Impedimetric Immunosensor for Sensitive Detection of Atrazine
    Electrochimica Acta 2010, 55, 6228-6232.

    13. C. Gondran, M. Orio, D. Rigal, B. Galland, L. Bouffier, T. Gulon, S. Cosnier
    Electropolymerized Biotinylated Poly(Pyrrole-Viologen) Film as Platform for the Development of Reagentless Impedimetric Immunosensors
    Electrochemistry Communications 2010, 12, 311-314.

    12. W. Haiss, S. Martin, L. E. Scullion, L. Bouffier, S. J. Higgins, R. J. Nichols
    Anomalous Length and Voltage Dependence of Single Molecule Conductance [HOT PAPER]
    Physical Chemistry Chemical Physics 2009, 11, 10831-10838.

    11. L. Bouffier, R. Dinica, J. Debray, P. Dumy, M. Demeumynck
    Functionalization of A Ring of Pyridoacridine as a Route Toward Greater Structural Diversity. Synthesis of an Octacyclic Analogue of Eilatin
    Bioorganic & Medicinal Chemistry Letters 2009, 19, 4836-4838.

    10. T. Doneux, L. Bouffier, L. V. Mello, D. J. Rigden, I. Kejnovska, D. G. Fernig, S. J. Higgins, R. J. Nichols
    Molecular Dynamics and Electrochemical Investigations of a pH-Responsive Peptide Monolayer
    Journal of Physical Chemistry C 2009, 113, 6792-6799.

    9. W. Haiss, S. Martin, E. Leary, H. Van Zalinge, S. J. Higgins, L. Bouffier, R. J. Nichols
    Elucidating the Role of Contact Morphology in Single Molecule Conductance
    Journal of Physical Chemistry C 2009, 113, 5823-5833.

    8. M. Holzinger, L. Bouffier, R. Villalonga, S. Cosnier
    Adamantane/Beta-Cyclodextrin Affinity Biosensors Based on Single-Walled Carbon Nanotubes
    Biosensors & Bioelectronics 2009, 24, 1128-1134.

    7. R. E. Ionescu, N. Jaffrezic-Renault, L. Bouffier, C. Gondran, S. Cosnier, D. G. Pinacho, M. Pilar Marco, F. J. Sanchez-Baeza, T. Healy, C. Martelet
    Impedimetric Immunosensor for the Specific Label Free Detection of Ciprofloxacin Antibiotic
    Biosensors & Bioelectronics 2007, 23, 549-555.

    6. L. Bouffier, M. Demeunynck, P. Dumy, C. Moucheron, A. Kirsch-De Mesmaeker
    A New Angular Planar Ligand - Synthesis, Characterization and Study of the Corresponding Ru(II) Complex and DNA Interaction
    Inorganic Chimica Acta 2007, 360, 3162-3168.

    5. S. Cosnier, R. E. Ionescu, S. Herrmann, L. Bouffier, M. Demeunynck, R. S. Marks
    An Electro-Enzymatic Polypyrrole-Intercalator Sensor for Determination of the West Nile Virus DNA
    Analytical Chemistry 2006, 78, 7054-7057.

    4. L. Bouffier, B. Baldeyrou, M.-P. Hildebrant, A. Lansiaux, M.-H. David-Cordonnier, D. Carrez, A. Croisy, O. Renaudet, P. Dumy, M. Demeunynck
    Amino- and Glycoconjugates of Pyrido[4,3,2-kl]Acridine. Synthesis, Antitumor Activity and DNA Binding
    Bioorganic & Medicinal Chemistry 2006, 14, 7520-7530.

    3. S. Szunerits, L. Bouffier, R. Calemczuk, B. Corso, M. Demeunynck, E. Descamps, Y. Defontaine, J.-B. Fiche, E. Fortin, T. Livache, P. Mailley, A. Roget, E. Viei
    Comparison of Different Strategies on DNA Chip Fabrication and DNA-Sensing : Optical and Electrochemical Approaches
    Electroanalysis 2005, 17, 2001-2017.

    2. L. Bouffier, M. Demeunynck, A. Milet, P. Dumy
    Reactivity of Pyrido[4,3,2-kl]Acridines : Regioselective Formation of 6-Substituted Derivatives
    Journal of Organic Chemistry 2004, 69, 8144-8147.

    1. B. Wang, L. Bouffier, M. Demeunynck, P. Mailley, A. Roget, T. Livache, P. Dumy
    New Acridone Derivatives for the Electrochemical DNA-Hybridisation Labelling
    Bioelectrochemistry 2004, 63, 233-237.