Mme BIBAL Brigitte

Téléphone 05 40 00 33 64

Groupe de recherche Nano-structures Organiques

Statut Permanent

Poste Enseignant-chercheur

Batiment A12

Etage 1° Est

ORCID ID: 0000-0003-0146-8396
Researchgate: https://www.researchgate.net/profile/Brigitte-Bibal
Keywords: Organic Chemistry, Organocatalysis and Gold Catalysis, Supramolecular Chemistry

RESEARCH ACTIVITIES
1) Supramolecular Catalysis:
- Organocatalysis
- Gold Catalysis
- Singlet Oxygen
2) Polyaromatic Receptors:
- Design, Synthesis, Binding properties
- Photo-modulation of Aromatic & Polyaromatic Receptors
- Recognition of Biological Species

SCIENTIFIC BACKGROUND
- Since 2020, Full Professor at the University of Bordeaux, Organic Chemistry Department
- 2003-2020 : Assistant then Associate Professor at University of Bordeaux
- 2002: Postdoctoral position, Pr Leon Ghosez's group (IECB, Bordeaux), Organic Synthesis.
- 2000 - 2001: Postdoctoral position, Pr Anthony Barrett's group (Imperial College, London), Organic Synthesis.
- 1997 - 2000: Ph. D. of Chemistry from Ecole Normale Supérieure de Lyon (UMR 5532) under guidance of Dr J.-P. Dutasta, Supramolecular Chemistry.
- 1997 : Undergraduate Studies at the School of Chemistry in Lyon (Ecole Supérieure de Chimie Industrielle de Lyon, ESCIL), France.

COVERS
- Chem. Sci. 2020, 11, 1478-1484: Photoinduced Reversible Covalent Modulation of Functional Organic Cages using Singlet Oxygen. https://pubs.rsc.org/en/content/articlelanding/2020/sc/c9sc05354a
- Chem. Eur. J. 2010, 16, 4196-4205: (Thio)amido-Indoles and (Thio)amido-Benzimidazoles: an Investigation of their Hydrogen-bonding and Organocatalytic Properties in the ROP of Lactide. https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/chem.200902912

Publications

Bouteille, Q., Davies, C., Labourdette, G., Bibal, B. (2024). Silver(I)-Catalyzed Syntheses of Triarylmethanes (TRAMs). In European Journal of Organic Chemistry (Vol. 27, Issue 47, p. e202400877). https://doi.org/10.1002/ejoc.202400877

Cayla, M., Sonet, D., Tarayre, E., Bapt, R., Bibal, B. (2023). Tandem Oxidative Dearomatizations of Diphenylanthracene Atropisomers. In Journal of Organic Chemistry (Vol. 88, Issue 18, p. 13067-13075). https://doi.org/10.1021/acs.joc.3c01252

Bouteille, Q., Sonet, D., Hennebelle, M., Desvergne, J.P., Morvan, E., Scalabre, A., Pouget, E., Méreau, R., Bibal, B. (2023). Singlet Oxygen Responsive Molecular Receptor to Modulate Atropisomerism and Cation Binding. In Chemistry A European Journal (Vol. 29, Issue 12, p. e202203210). https://doi.org/10.1002/chem.202203210

Sonet, D., Cayla, M., Méreau, R., Morvan, E., Lacoudre, A., Vanthuyne, N., Albalat, M., Bassani, D.M., Scalabre, A., Pouget, E., Bibal, B. (2022). Chiral Anthranyl Trifluoromethyl Alcohols: Structures, Oxidative Dearomatization and Chiroptical Properties. In Chemistry A European Journal (Vol. 28, Issue 72, p. e202202695). https://doi.org/10.1002/chem.202202695

Cao, Z., Scalabre, A., Nlate, S., Buffière, S., Oda, R., Pouget, E., Bibal, B. (2021). Silica-Supported Phosphine–Gold Complexes as an Efficient Catalytic System for a Dearomative Spirocyclization. In Chemistry A European Journal (Vol. 27, Issue 1, p. 427-433). https://doi.org/10.1002/chem.202004251

Houle, C., Savoie, P.R., Davies, C., Jardel, D., Champagne, P.A., Bibal, B., Paquin, J.F. (2020). Thiourea-Catalyzed C−F Bond Activation: Amination of Benzylic Fluorides. In Chemistry A European Journal (Vol. 26, Issue 46, p. 10620-10625). https://doi.org/10.1002/chem.202001905

Mongin, C., Ardoy, A.M., Méreau, R., Bassani, D.M., Bibal, B. (2020). Singlet oxygen stimulus for switchable functional organic cages. In Chemical Science (Vol. 11, Issue 6, p. 1478-1484). https://doi.org/10.1039/c9sc05354a

Cao, Z., Bassani, D.M., Bibal, B. (2020). Light activation of gold complexes. In Photochemistry (Vol. 47, p. 423-456). https://doi.org/10.1039/9781788016520-00421

Cao, Z., Lacoudre, A., Rossy, C., Bibal, B. (2019). Self-assembled coordination thioether silver(I) macrocyclic complexes for homogeneous catalysis. In Beilstein Journal of Organic Chemistry (Vol. 15, p. 2465-2472). https://doi.org/10.3762/bjoc.15.239

Sonet, D., Bibal, B. (2019). Triphenylene: A versatile molecular receptor. In Tetrahedron Letters (Vol. 60, Issue 12, p. 872-884). https://doi.org/10.1016/j.tetlet.2019.02.033

Cao, Z., Bassani, D.M., Bibal, B. (2018). Photoreduction of Thioether Gold(III) Complexes: Mechanistic Insight and Homogeneous Catalysis. In Chemistry A European Journal (Vol. 24, Issue 70, p. 18779-18787). https://doi.org/10.1002/chem.201804322

Pisciottani, L., Douarre, M., Bibal, B., Davies, C., Roberts, H., Kauffmann, B., Horswell, S.L., Tucker, J.H.R., McClenaghan, N.D. (2018). Macrocyclic Hamilton-type receptors comprising a ferrocene pivot. In Supramolecular Chemistry (Vol. 30, Issue 10, p. 869-875). https://doi.org/10.1080/10610278.2018.1426856

Bibal, B. (2018). Acetylcholine receptors in water. In Supramolecular Chemistry (Vol. 30, Issue 4, p. 243-254). https://doi.org/10.1080/10610278.2017.1342823

Koeller, S., Lescure, M.H., Davies, C., Desvergne, J.P., Massip, S., Bibal, B. (2017). Hydrogen-Bonding Amidoindoles in the Presence of Anions: An X-ray Structure of a Receptor at the Acid–Base Half-Equivalence that Binds an Anion. In European Journal of Organic Chemistry (Vol. 2017, Issue 37, p. 5627-5631). https://doi.org/10.1002/ejoc.201701040

Anastasaki, A., Bibal, B., Boyer, C., Chen, G., De, P., Guillaume, S., Huang, X., Kumarasamy, E., Xu, F.J., Zhao, Y. (2017). Outstanding Reviewers for: Polymer Chemistry in 2016. In Polymer Chemistry (Vol. 8, Issue 13, p. 1998). https://doi.org/10.1039/c7py90044a

Mongin, C., Liang, C.K., Bibal, B., Bassani, D.M. (2017). A supramolecular approach to controlling the behavior of excited states. In Pure and Applied Chemistry (Vol. 89, Issue 2, p. 269-277). https://doi.org/10.1515/pac-2016-1106

Koeller, S., Lescure, M.H., Davies, C., Desvergne, J.P., Massip, S., Bibal, B. (2017). Insight into the deprotonation at the half-equivalence point of (thio)amido-benzimidazoles in the presence of anions. In Organic and Biomolecular Chemistry (Vol. 15, Issue 35, p. 7263-7266). https://doi.org/10.1039/c7ob01704a

Jardel, D., Davies, C., Peruch, F., Massip, S., Bibal, B. (2016). Protonated Phosphazenes: Structures and Hydrogen-Bonding Organocatalysts for Carbonyl Bond Activation. In Advanced Synthesis and Catalysis (Vol. 358, Issue 7, p. 1110-1118). https://doi.org/10.1002/adsc.201600062

Zhang, D., Jardel, D., Peruch, F., Calin, N., Dufaud, V., Dutasta, J.P., Martinez, A., Bibal, B. (2016). Azaphosphatranes as Hydrogen-Bonding Organocatalysts for the Activation of Carbonyl Groups: Investigation of Lactide Ring-Opening Polymerization. In European Journal of Organic Chemistry (Vol. 2016, Issue 8, p. 1619-1624). https://doi.org/10.1002/ejoc.201600080

Mongin, C., Pianet, I., Jonusauskas, G., Bassani, D.M., Bibal, B. (2015). Supramolecular Photocatalyst for the Reduction of Au(III) to Au(I) and High-Turnover Generation of Gold Nanocrystals. In ACS Catalysis (Vol. 5, Issue 1, p. 380-387). https://doi.org/10.1021/cs5016063

Bibal, B., Mongin, C., Bassani, D.M. (2014). Template effects and supramolecular control of photoreactions in solution. In Chemical Society Reviews (Vol. 43, Issue 12, p. 4179-4198). https://doi.org/10.1039/c3cs60366k

Koeller, S., Thomas, C., Peruch, F., Deffieux, A., Massip, S., Léger, J.M., Desvergne, J.P., Milet, A., Bibal, B. (2014). α-Halogenoacetanilides as hydrogen-bonding organocatalysts that activate carbonyl bonds: Fluorine versus chlorine and bromine. In Chemistry A European Journal (Vol. 20, Issue 10, p. 2849-2859). https://doi.org/10.1002/chem.201303662

Thomas, C., Brut, S., Bibal, B. (2014). Quaternary ammoniums and a cationic sodium complex as supramolecular catalysts in ring-opening of epoxides by amines. In Tetrahedron (Vol. 70, Issue 8, p. 1646-1650). https://doi.org/10.1016/j.tet.2014.01.018

Kadota, J., Pavlović, D., Hirano, H., Okada, A., Agari, Y., Bibal, B., Deffieux, A., Peruch, F. (2014). Controlled bulk polymerization of l-lactide and lactones by dual activation with organo-catalytic systems. In Rsc Advances (Vol. 4, Issue 28, p. 14725-14732). https://doi.org/10.1039/c4ra01239a

Thomas, C., Bibal, B. (2014). Hydrogen-bonding organocatalysts for ring-opening polymerization. In Green Chemistry (Vol. 16, Issue 4, p. 1687-1699). https://doi.org/10.1039/c3gc41806e

Mettra, B., Bretonnière, Y., Mulatier, J.C., Bibal, B., Tinant, B., Aronica, C., Dutasta, J.P. (2013). Design of differently P-substituted 4i PO fluorescent tetraphosphonate cavitands. In Supramolecular Chemistry (Vol. 25, Issue 9-11, p. 672-681). https://doi.org/10.1080/10610278.2013.822975

Thomas, C., Milet, A., Peruch, F., Bibal, B. (2013). Activation of carbonyl bonds by quaternary ammoniums and a (Na +:crown-ether) complex: Investigation of the ring-opening polymerization of cyclic esters. In Polymer Chemistry (Vol. 4, Issue 12, p. 3491-3498). https://doi.org/10.1039/c3py00304c

Thomas, C., Peruch, F., Bibal, B. (2012). Ring-opening polymerization of lactones using supramolecular organocatalysts under simple conditions. In Rsc Advances (Vol. 2, Issue 33, p. 12851-12856). https://doi.org/10.1039/c2ra22535b

Givelet, C., Bibal, B. (2011). A simple ionic triphenylene receptor for catecholamines, serotonin and d-glucosamine in buffered water. In Organic and Biomolecular Chemistry (Vol. 9, Issue 21, p. 7457-7460). https://doi.org/10.1039/c1ob06099f

Thomas, C., Peruch, F., Deffieux, A., Milet, A., Desvergne, J.P., Bibal, B. (2011). Phenols and tertiary amines: An amazingly simple hydrogen-bonding organocatalytic system promoting ring opening polymerization. In Advanced Synthesis and Catalysis (Vol. 353, Issue 7, p. 1049-1054). https://doi.org/10.1002/adsc.201100013

Kadota, J., Koeller, S., Pavlović, D., Desvergne, J.P., Bibal, B., Peruch, F., Deffieux, A. (2011). Controlled ring-opening polymerization of L-lactide triggered by supramolecular organocatalytic systems. In ACS Symposium Series (Vol. 1063, p. 153-168). https://doi.org/10.1021/bk-2011-1063.ch010

Kadota, J., Pavlović, D., Desvergne, J.P., Bibal, B., Peruch, F., Deffieux, A. (2010). Ring-opening polymerization of l-lactide catalyzed by an organocatalytic system combining acidic and basic sites. In Macromolecules (Vol. 43, Issue 21, p. 8874-8879). https://doi.org/10.1021/ma101688d

Koeller, S., Kadota, J., Peruch, F., Deffieux, A., Pinaud, N., Pianet, I., Massip, S., Léger, J.M., Desvergne, J.P., Bibal, B. (2010). (Thio)amidoindoles and (Thio)amidobenzimidazoles: An investigation of their hydrogen-bonding and organocatalytic properties in the ringopening polymerization of lactide. In Chemistry A European Journal (Vol. 16, Issue 14, p. 4196-4205). https://doi.org/10.1002/chem.200902912

Koeller, S., Kadota, J., Deffieux, A., Peruch, F., Massip, S., Léger, J.M., Desvergne, J.P., Bibal, B. (2009). Ring-opening polymerization of L-lactide efficiently triggered by an amido-indole. X-ray structure of a complex between L-lactide and the hydrogen-bonding organocatalyst. In Journal of the American Chemical Society (Vol. 131, Issue 42, p. 15088-15089). https://doi.org/10.1021/ja906119t

Givelet, C., Buffeteau, T., Arnaud-Neu, F., Hubscher-Bruder, V., Bibal, B. (2009). A hydrosoluble triphenylene that preferentially binds acetylcholine, epibatidine, and nicotine. In Journal of Organic Chemistry (Vol. 74, Issue 14, p. 5059-5062). https://doi.org/10.1021/jo900683x

Givelet, C., Tinant, B., Van Meervelt, L., Buffeteau, T., Marchand-Geneste, N., Bibal, B. (2009). Polyphosphorylated Triphenylenes: Synthesis, Crystal Structure, and Selective Catechol Recognition. In Journal of Organic Chemistry (Vol. 74, Issue 2, p. 652-659). https://doi.org/10.1021/jo802015k

Dumartin, M.L., Givelet, C., Meyrand, P., Bibal, B., Gosse, I. (2009). A fluorescent cyclotriveratrylene: Synthesis, emission properties and acetylcholine recognition in water. In Organic and Biomolecular Chemistry (Vol. 7, Issue 13, p. 2725-2728). https://doi.org/10.1039/b904590b

Barrett, A.G.M., Bibal, B., Hopkins, B.T., Köbberling, J., Love, A.C., Tedeschi, L. (2005). Facile and purification free synthesis of peptides utilizing ROMPgel- and ROMPsphere-supported coupling reagents. In Tetrahedron (Vol. 61, Issue 51, p. 12033-12041). https://doi.org/10.1016/j.tet.2005.06.120

Bibal, B., Declercq, J.P., Dutasta, J.P., Tinant, B., Valade, A.G. (2003). Thiophosphorylated cavitand: Structure and affinity towards soft metal ions. In Tetrahedron (Vol. 59, Issue 31, p. 5849-5854). https://doi.org/10.1016/S0040-4020(03)00946-3

Bibal, B., Tinant, B., Declercq, J.P., Dutasta, J.P. (2003). Preparation and structure of [iiii] tetraphosphonatocavitands bearing long chain functionality at the lower rim: Metal picrates extraction studies. In Supramolecular Chemistry (Vol. 15, Issue 1, p. 25-32). https://doi.org/10.1080/1061027021000002396

Dutasta, J.P., Bibal, B., Declercq, J.P., Dubessy, B., Mulatier, J.C., Tinant, B., Valade, A.G. (2002). Supramolecular assemblies of phosphorylated cavitands. In Phosphorus Sulfur and Silicon and Related Elements (Vol. 177, Issue 6-7, p. 1485-1488). https://doi.org/10.1080/10426500212313

Bibal, B., Tinant, B., Declercq, J.P., Dutasta, J.P. (2002). A new supramolecular assembly obtained from the combination of silver(I) cations with a thiophosphorylated cavitand. In Chemical Communications (Vol. 5, p. 432-433). https://doi.org/10.1039/b110698h

Nebois, P., Sarciron, M.E., Bibal, B., Bouammali, B., Cherkaoui, O., Pautet, F., Pétavy, A.F., Walchshofer, N., Fillion, H. (2000). Quinonic derivatives active against a virulent strain of Toxoplasma gondii. Synthesis of 2-methylfuro[2,3-g]- and [3,2-g]isoquinolinetriones. In Bioorganic and Medicinal Chemistry Letters (Vol. 10, Issue 9, p. 871-873). https://doi.org/10.1016/S0960-894X(00)00112-8

Dutasta, J.P., Bibal, B., Delangle, P., Gosse, I., Mulatier, J.C. (1999). Synthesis, host properties and structure of phosphorylated cavitands. In Phosphorus Sulfur and Silicon and Related Elements (Vol. 144-146, p. 337-341). https://doi.org/10.1080/10426509908546250