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Téléphone
05 40 00 30 12
Groupe de recherche
Synthèse organique et substances naturelles
Statut
Permanent
Poste
Enseignant-chercheur
Batiment
A12
Etage
RDC Ouest
Publications
(). Total Synthesis of (−)-Vescalagin, the Iconic Member of the C-Glucosidic Ellagitannin Family. In Chemistry A European Journal (Vol. 31, Issue 34, p. e202501159). https://doi.org/10.1002/chem.202501159
(). Copper(II)-Amine Complex-Mediated Intramolecular Coupling of Gallates: A Bioinspired Solution to the Atroposelective Synthesis of Ellagitannins. In Angewandte Chemie International Edition (Vol. 63, Issue 52, p. e202412036). https://doi.org/10.1002/anie.202412036
(). Synthesis of obovatol and related neolignan analogues as α-glucosidase and α-amylase inhibitors. In Bioorganic Chemistry (Vol. 147, p. 107392). https://doi.org/10.1016/j.bioorg.2024.107392
(). Systemic Convergent Multitarget Interactions of Plant Polyphenols Revealed by Affinity-Based Protein Profiling of Bone Cells Using C-Glucosidic Vescal(ag)in-Bearing Chemoproteomic Probes. In ACS Chemical Biology (Vol. 18, Issue 12, p. 2495-2505). https://doi.org/10.1021/acschembio.3c00440
(). Synthesis of Flavonol-Bearing Probes for Chemoproteomic and Bioinformatic Analyses of Asteraceae Petals in Search of Novel Flavonoid Enzymes. In International Journal of Molecular Sciences (Vol. 24, Issue 11, p. 9724). https://doi.org/10.3390/ijms24119724
(). Preparation of a ε-caprolactonic diterpenoid derivate by unexpected oxidative cleavage/lactonization of 2-oxoaustroeupatol. In Natural Products and Bioprospecting (Vol. 12, Issue 1, p. 20). https://doi.org/10.1007/s13659-022-00343-2
(). Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage. In Pharmaceuticals (Vol. 15, Issue 10, p. 1234). https://doi.org/10.3390/ph15101234
(). Bispericyclic Diels–Alder Dimerization of ortho-Quinols in Natural Product (Bio)Synthesis: Bioinspired Chemical 6-Step Synthesis of (+)-Maytenone. In Angewandte Chemie International Edition (Vol. 60, Issue 27, p. 14967-14974). https://doi.org/10.1002/anie.202103410
(). Real-Time Analysis of Polyphenol–Protein Interactions by Surface Plasmon Resonance Using Surface-Bound Polyphenols. In Chemistry A European Journal (Vol. 27, Issue 17, p. 5498-5508). https://doi.org/10.1002/chem.202005187
(). Maternal alcoholism and neonatal hypoxia-ischemia: Neuroprotection by stilbenoid polyphenols. In Brain Research (Vol. 1738, p. 146798). https://doi.org/10.1016/j.brainres.2020.146798
(). C-glucosidic ellagitannins and galloylated glucoses as potential functional food ingredients with anti-diabetic properties: a study of α-glucosidase and α-amylase inhibition. In Food Chemistry (Vol. 313, p. 126099). https://doi.org/10.1016/j.foodchem.2019.126099
(). Synthesis and leishmanicidal evaluation of sulfanyl- and sulfonyl-tethered functionalized benzoate derivatives featuring a nitroimidazole moiety. In Archiv Der Pharmazie (Vol. 353, Issue 5, p. e2000002). https://doi.org/10.1002/ardp.202000002
(). Bio-inspired Total Synthesis of Twelve Securinega Alkaloids: Structural Reassignments of (+)-Virosine B and (−)-Episecurinol A. In Chemistry A European Journal (Vol. 25, Issue 49, p. 11574-11580). https://doi.org/10.1002/chem.201903122
(). Interaction between Ellagitannins and Salivary Proline-Rich Proteins. In Journal of Agricultural and Food Chemistry (Vol. 67, Issue 34, p. 9579-9590). https://doi.org/10.1021/acs.jafc.9b02574
(). Hemisynthesis and Bactericidal Activity of Several Substituted Benzoic Acid Esters of 13(S)-Labdan-8α,15-Diol, a Diterpene from Oxylobus glanduliferus. In Chemistry of Natural Compounds (Vol. 55, Issue 4, p. 677-684). https://doi.org/10.1007/s10600-019-02777-6
(). Synthesis of [7]Helicene Enantiomers and Exploratory Study of Their Conversion into Helically Chiral Iodoarenes and Iodanes. In Chemistry A European Journal (Vol. 25, Issue 11, p. 2852-2858). https://doi.org/10.1002/chem.201805761
(). Preparation and bactericidal activity of oxidation derivatives of austroeupatol, an ent-nor-furano diterpenoid of the labdane series from Austroeupatorium inulifolium. In Phytochemistry Letters (Vol. 29, p. 47-52). https://doi.org/10.1016/j.phytol.2018.11.007
(). Reactivity of wine polyphenols under oxidation conditions: Hemisynthesis of adducts between grape catechins or oak ellagitannins and odoriferous thiols. In Tetrahedron (Vol. 75, Issue 5, p. 551-560). https://doi.org/10.1016/j.tet.2018.11.071
(). Anti-Herpes Simplex Virus Type 1 Activity of Specially Selected Groups of Tannins. In Drug Research (Vol. 69, Issue 7, p. 374-381). https://doi.org/10.1055/a-0640-2557
(). Rapid Screening of Ellagitannins in Natural Sources via Targeted Reporter Ion Triggered Tandem Mass Spectrometry. In Scientific Reports (Vol. 8, Issue 1, p. 10399). https://doi.org/10.1038/s41598-018-27708-3
(). Anti-osteoclastic effects of C-glucosidic ellagitannins mediated by actin perturbation. In European Journal of Cell Biology (Vol. 97, Issue 8, p. 533-545). https://doi.org/10.1016/j.ejcb.2018.09.003
(). Synthesis of Scyphostatin Analogues through Hypervalent Iodine-Mediated Phenol Dearomatization. In Journal of Organic Chemistry (Vol. 82, Issue 22, p. 11816-11828). https://doi.org/10.1021/acs.joc.7b02366
(). Bioinspired Total Synthesis of (−)-Vescalin: A Nonahydroxytriphenoylated C-Glucosidic Ellagitannin. In Angewandte Chemie International Edition (Vol. 56, Issue 44, p. 13833-13837). https://doi.org/10.1002/anie.201707613
(). Phenol dearomatization with hypervalent iodine reagents. In Topics in Current Chemistry (Vol. 373, p. 25-74). https://doi.org/10.1007/128_2015_665
(). Immobilization of flavan-3-ols onto sensor chips to study their interactions with proteins and pectins by SPR. In Applied Surface Science (Vol. 371, p. 512-518). https://doi.org/10.1016/j.apsusc.2016.03.002
(). Gallotannins and Tannic Acid: First Chemical Syntheses and in Vitro Inhibitory Activity on Alzheimer's Amyloid β-Peptide Aggregation. In Angewandte Chemie International Edition (Vol. 54, Issue 28, p. 8217-8221). https://doi.org/10.1002/anie.201411606
(). Polyphenolic C-glucosidic ellagitannins present in oak-aged wine inhibit HIV-1 nucleocapsid protein. In Tetrahedron (Vol. 71, Issue 20, p. 3020-3026). https://doi.org/10.1016/j.tet.2015.01.035
(). About the impact of oak ellagitannins on wine odoriferous thiols under acidic and oxidation conditions. In Tetrahedron (Vol. 71, Issue 20, p. 2991-2998). https://doi.org/10.1016/j.tet.2015.02.036
(). New affinity-based probes for capturing flavonoid-binding proteins. In Chemical Communications (Vol. 50, Issue 67, p. 9387-9389). https://doi.org/10.1039/c4cc04557b
(). Facile and sustainable synthesis of the natural antioxidant hydroxytyrosol. In Tetrahedron Letters (Vol. 55, Issue 15, p. 2455-2458). https://doi.org/10.1016/j.tetlet.2014.02.134
(). Oxidative Coupling of Phenols and Phenol Ethers. In Comprehensive Organic Synthesis Second Edition (Vol. 3, p. 656-740). https://doi.org/10.1016/B978-0-08-097742-3.00318-9
(). Protecting-group-free solid-phase anchoring of polyphenolic C-glucosidic ellagitannins and synthesis of 1-alkylamino-vescalagin derivatives. In European Journal of Organic Chemistry (Vol. 2014, Issue 23, p. 4963-4972). https://doi.org/10.1002/ejoc.201402444
(). Remarkable biomimetic chemoselective aerobic oxidation of flavano-ellagitannins found in oak-aged wine. In Angewandte Chemie International Edition (Vol. 52, Issue 44, p. 11530-11533). https://doi.org/10.1002/anie.201305839
(). Hydrolyzable tannins: Gallotannins and ellagitannins. In Natural Products Phytochemistry Botany and Metabolism of Alkaloids Phenolics and Terpenes (p. 1975-2010). https://doi.org/10.1007/978-3-642-22144-6_65
(). Synthetic studies toward c-glucosidic ellagitannins: A biomimetic total synthesis of 5-O-desgalloylepipunicacortein A. In Chemistry A European Journal (Vol. 18, Issue 29, p. 9063-9074). https://doi.org/10.1002/chem.201200517
(). Resveratrol still has something to say about aging!. In Angewandte Chemie International Edition (Vol. 51, Issue 28, p. 6824-6826). https://doi.org/10.1002/anie.201203059
(). The polyphenolic ellagitannin vescalagin acts as a preferential catalytic inhibitor of the α isoform of human DNA topoisomerase II. In Molecular Pharmacology (Vol. 82, Issue 1, p. 134-141). https://doi.org/10.1124/mol.111.077537
(). Synthesis of Biologically Active Catecholic Compounds via ortho-Selective Oxygenation of Phenolic Compounds Using Hypervalent Iodine(V) Reagents. In Current Organic Synthesis (Vol. 9, Issue 5, p. 650-669). https://doi.org/10.2174/157017912803251792
(). First and biomimetic total synthesis of a member of the C-glucosidic subclass of ellagitannins, 5-O-desgalloylepipunicacortein A. In Chemical Communications (Vol. 47, Issue 5, p. 1628-1630). https://doi.org/10.1039/c0cc04007j
(). Plant polyphenols: Chemical properties, biological activities, and synthesis. In Angewandte Chemie International Edition (Vol. 50, Issue 3, p. 586-621). https://doi.org/10.1002/anie.201000044
(). Synthesis of ellagitannin natural products. In Natural Product Reports (Vol. 28, Issue 5, p. 853-874). https://doi.org/10.1039/c0np00058b
(). Development of an Affinity-Based Proteomic Strategy for the Elucidation of Proanthocyanidin Biosynthesis. In Chembiochem (Vol. 12, Issue 8, p. 1193-1197). https://doi.org/10.1002/cbic.201100044
(). Hypervalent iodine-mediated oxygenative phenol dearomatization reactions. In Tetrahedron (Vol. 66, Issue 31, p. 5908-5917). https://doi.org/10.1016/j.tet.2010.05.078
(). Hypervalent iodine-mediated phenol dearomatization in natural product synthesis. In Tetrahedron (Vol. 66, Issue 13, p. 2235-2261). https://doi.org/10.1016/j.tet.2009.12.046
(). Stable solid-supported leucoanthocyanidin variants for flavanoid biosynthesis elucidation. In Tetrahedron Letters (Vol. 50, Issue 47, p. 6567-6571). https://doi.org/10.1016/j.tetlet.2009.09.045
(). Oxidative dearomatization of phenols: Why, how and what for?. In Synlett (Issue 4, p. 467-495). https://doi.org/10.1055/s-2008-1032094
(). Regio- and stereoselectivities in Diels-Alder cyclodimerizations of orthoquinonoid cyclohexa-2,4-dienones. In Tetrahedron (Vol. 63, Issue 28, p. 6493-6505). https://doi.org/10.1016/j.tet.2007.03.035
(). Electrochemical synthesis of dimerizing and nondimerizing orthoquinone monoketals. In Journal of Organic Chemistry (Vol. 69, Issue 25, p. 8731-8738). https://doi.org/10.1021/jo048677i
(). First asymmetric synthesis of orthoquinone monoketal enantiomers via anodic oxidation. In Organic Letters (Vol. 6, Issue 24, p. 4571-4573). https://doi.org/10.1021/ol048030k
(). Chemical and electrochemical oxidative activation of arenol derivatives for carbon-carbon bond formation. In Current Organic Chemistry (Vol. 8, Issue 2, p. 113-148). https://doi.org/10.2174/1385272043486016
(). Electrochemically-induced spirolactonization of α-(methoxyphenoxy)alkanoic acids into quinone ketals. In Journal of Organic Chemistry (Vol. 67, Issue 13, p. 4458-4465). https://doi.org/10.1021/jo020023r
(). Electrochemical preparation of tris(tert-butyldimethylsilyl)cyclopropene and its hydride abstraction to tris(tert-butyldimethylsilyl)cyclopropenium tetrafluoroborate. In Proceedings of the National Academy of Sciences of the United States of America (Vol. 96, Issue 18, p. 10003-10005). https://doi.org/10.1073/pnas.96.18.10003
(). Investigations on computed 13C NMR one-dimensional non-refocused INEPT experiments for structural determinations in O-methylated glycosides. In Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy (Vol. 55, Issue 12, p. 2383-2391). https://doi.org/10.1016/S1386-1425(99)00025-6
(). Preparation of and fluoroalkylation with (chlorodifluoromethyl)trimethylsilane, difluorobis(trimethylsilyl)methane, and 1,1,2,2-tetrafluoro-1,2-bis(trimethylsilyl)ethane. In Journal of the American Chemical Society (Vol. 119, Issue 7, p. 1572-1581). https://doi.org/10.1021/ja962990n
(). Acidity dependence of the trifluoromethanesulfonic acid catalyzed isobutane-isobutylene alkylation modified with trifluoroacetic acid or water. In Applied Catalysis A General (Vol. 146, Issue 1, p. 107-117). https://doi.org/10.1016/0926-860X(96)00045-2
(). Selective electrochemical mono- and polysilylation of halothiophenes. In Organometallics (Vol. 15, Issue 8, p. 2041-2046). https://doi.org/10.1021/om950605h
(). Facile Preparation of (Trifluoromethyl)tributyltin and Transtrifluoromethylation of Disilyl Sulfides to the Corresponding Trifluoromethylsilanes. In Synlett (Vol. 1996, Issue 2, p. 151-153). https://doi.org/10.1055/s-1996-5355
(). L'électrosynthése à anode consommable: Quel apport pour la chimie organique du silicium ?. In Journal De Chimie Physique Et De Physico Chimie Biologique (Vol. 93, Issue 4, p. 591-600). https://doi.org/10.1051/jcp/1996930591
(). Convenient and Safe Electrochemical Synthesis of (Trifluoromethyl)trimethylsilane 1a. In Synlett (Vol. 1994, Issue 12, p. 1057-1058). https://doi.org/10.1055/s-1994-34986
(). Electrochemical Synthesis of Hexakis(trimethylsilyl)-3,3′-bicyclopropenyl. In Journal of Organic Chemistry (Vol. 59, Issue 24, p. 7532-7533). https://doi.org/10.1021/jo00103a062
(). Selective Electrochemical Trimethylsilylation of Tetrachlorocyclopropene to 1-(Trimethylsilyl)-trichlorocyclopropene, a New Cyclopropene Building Block 1. In Synlett (Vol. 1994, Issue 10, p. 819-820). https://doi.org/10.1055/s-1994-23015
(). Reductive Electrochemical Silylation of Unsaturated Nitrogen Functionalities: A Simple and Efficient Synthesis of Precursors of Bis(trimethylsilyl)methylamine. In Organometallics (Vol. 13, Issue 9, p. 3711-3714). https://doi.org/10.1021/om00021a051
(). Electrochemical Trimethylsilylation of o-Dichlorobenzene: A Selective Route to Silylated Cyclo-C6 Synthons. In Organometallics (Vol. 13, Issue 6, p. 2415-2422). https://doi.org/10.1021/om00018a039